My Switch to Estradiol After a Year on Phytoestrogens
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Hormone Replacement Therapy Gel
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Hormone Replacement Therapy Gel

This Estradiol Gel is a topical solution for hormone replacement therapy. It's designed to provide relief from menopause symptoms, such as hot flashes and night sweats, and promote overall well-being. With its convenient gel formula, you can easily apply it directly to your skin for quick absorption. I've seen it work wonders for women who've tried it - it's a game-changer for managing those pesky symptoms.
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My Switch to Estradiol After a Year on Phytoestrogens

summarizeEditor's Summary

After a year of dealing with the ups and downs of phytoestrogens, I decided to give Estradiol Gel a shot. My gynecologist-endocrinologist initially prescribed Estrogen Gel to help alleviate hot flashes and mood swings. I was impressed by the gel form and easy dose measurements - it made using it a breeze. The significant reduction in symptoms was a total game changer for me, and I'm glad I made the switch. However, I did experience some skin irritation, especially on sensitive areas, which I'll get into below. Overall, Estradiol Gel has been a total lifesaver for me, and I'm so glad I made the switch.

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Kararİyi
Kalite9/10
Etkinlik8/10
Faydalilik7/10
I was prescribed Estrogen Gel by my gynecologist-endocrinologist a year after the first menopause symptoms appeared. At the time, I was experiencing hot flashes and mood swings, so I was mentally prepared for hormone therapy.
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But before starting hormone therapy, I needed a thorough check-up to ensure it was safe. After all the necessary tests, I was first suggested to start with phytoestrogens, as my blood hormone analysis still showed it was too early for hormone replacement therapy.
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I took isoflavones from soy, sacred vitex, wild yam, and red clover for a year, with regular check-ups every six months. I felt normal, but my estrogen levels were still low, and my follicle-stimulating hormone was high – a clear indication that I needed hormone replacement therapy.
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My doctor prescribed me Estrogen Gel, a transdermal gel that you apply to your skin.
Estrogen GelFrom the manufacturer:
The active ingredient in Estrogen Gel, 17β-estradiol, is chemically and biologically identical to the human endogenous estradiol.
It has an estrogenic effect on major target organs: ovaries, endometrium, vaginal epithelium, breast tissue, urethra, hypothalamus, pituitary gland, liver – similar to the action of endogenous estrogens in the follicular phase of the menstrual cycle.
It replenishes estrogen deficiencies in women during menopause and reduces the severity of menopausal symptoms, including hot flashes, excessive night sweats, and changes to the urinary tract (atrophic vaginitis, dyspareunia, incontinence), as well as emotional and psychological disturbances.
The clinical effectiveness of Estrogen Gel in treating menopausal symptoms is comparable to that of oral estrogens.
I've noticed that Estradiol helps lower overall cholesterol levels without affecting the ratio of LDL to HDL.
It has a pro-coagulant effect, increasing the synthesis in the liver of vitamin K-dependent clotting factors (II, VII, IX, X), and reducing the concentration of antithrombin III.
Estradiol prevents bone loss associated with natural menopause or oophorectomy.
Bone loss during postmenopause is linked to a decrease in mineral density (BMD) due to estrogen deficiency. The effect of estrogen on BMD is dose-dependent and appears to continue as long as hormone replacement therapy (HRT) is being administered. After HRT is discontinued, BMD starts to decrease at the same rate as before the treatment began.
xa0Hormonal medications Estradial gelIngredients per 1g gel:
Active ingredient: estradiol hemihydrate 0.62 mg, equivalent to estradiol 0.62 mg. Excipients: carbomer (carbopol 980) 5.0 mg, tromethamine (triethanolamine) 5.0 mg, ethanol 400 mg, purified water q.s. to 1 g.
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This medication comes in a clear gel form, packaged in a pump bottle with a built-in dosing mechanism. There's a thin nozzle that closes with an additional small cap.
xa0Hormonal medications Estradial gelThe gel is colorless and transparent, with a medium consistency. To dispense the right amount, I press the pump all the way down, and it releases a small amount – just the dosage I need.
Hormonal Medications Estrogele GelI used this product as part of my hormonal regimen, applying it daily from day 5 to 25 of my cycle. I started using it in April and have been applying it consistently for about half a year, with a five-day break in between.
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I began with the lowest dosage - one press - and applied it to my abdomen at first, but it wasn't very convenient since the skin is thicker and takes longer to absorb. So, I started applying it to the inner thigh area, making sure to avoid my chest and genital areas.
Hormonal Medications Estrogele GelThe skin on my thighs is thinner, so the gel absorbs much faster. As soon as I apply it, I can smell the ethanol, which is normal since it contains this ingredient. However, be careful not to apply it to any open wounds, as it can cause a stinging sensation.
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I don't need to massage the gel in - just spreading it across the area with two hands does the trick. Within 2-3 minutes, it's fully absorbed, leaving a slight tackiness behind. I apply the gel only in the evening, after my shower. I try to apply it at the same time every day to maintain a consistent level of estrogen in my blood.
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For those who haven't had a hysterectomy, it's essential to take progesterone alongside estrogen. My endocrinologist prescribed me 200mg of progesterone on the 16th day of my cycle, which I take for exactly 10 days.
Hormonal Supplements Estrogen GelWhen I was taking phytoestrogens, my cycle was irregular, and I had menopause symptoms that I needed to manage. I also took beta-alanine and 5-hydroxytryptophan on top of that. But as soon as I switched to estrogen gel and started applying it regularly with progesterone, my cycle became like clockwork.
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In the first cycle, my body was adjusting to estrogen again, I experienced some unpleasant symptoms before my period, my breasts were swollen, I had PMS symptoms, and I felt irritable. It was like I was transported back to my younger years.
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But after a few months, things got better. My overall feeling improved, and I felt like myself again - young, energetic, and not irritable. The dryness in my vaginal area disappeared, my breasts regained their former size, and my skin looked smoother. It's no wonder they say that as long as you have estrogen, you're still young.
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The manufacturer claims that the gel pack has 64 presses, which meant I should have enough for three cycles, or three months. And that's exactly what happened - the first pack lasted me three cycles, and I just finished the second pack and ordered the third.
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My doctor told me to come back in three months if I didn't feel great, or six months if everything was fine. I'm feeling good, so I'll be back in six months.
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Reviews on progesterone supplements:
When I was researching alternative options for hormonal therapy, I came across some pretty impressive reviews for Italfarmaco S.P.A. Iprenzo. People were raving about the results, and I was curious to see if it lived up to the hype.
Of course, there are plenty of other options out there, like Pradgisan, which seems to be a budget-friendly alternative to some of the other popular brands.
I was also interested in Laboratories Bézen International Urogestan, which claims to help with more than just fertility and menopause symptoms.
Another option I looked into was Solvay Pharma Dufaston, which seems to be a popular choice for regulating menstrual cycles.
But what about the herbal alternatives? I was intrigued by Sibella Klimo, which combines isoflavones with other natural ingredients to support women's health.
I also came across Fit and Joy, a vitamin complex that claims to help women feel younger and more energetic, thanks to its blend of wild yam and other natural ingredients.
And finally, I looked into Red Clover, a herbal supplement that's supposed to have a similar structure to isoflavones.
But one product that really caught my eye was Aquion Mense, which seems to offer a non-hormonal way to support women's health during menopause.

live_helpFeatured FAQ

What is Estradiol Gel, and how does it work?

Estradiol Gel is a transdermal estrogen replacement therapy that helps alleviate menopause symptoms by replacing estrogen in the body. It's applied topically to the skin, where it's absorbed into the bloodstream and helps regulate estrogen levels.

What are the benefits of using Estradiol Gel over phytoestrogens?

Estradiol Gel is a more direct and effective way to replace estrogen in the body, leading to faster symptom relief and improved overall health. It's also more convenient and easier to use than phytoestrogens.

Can I use Estradiol Gel if I have sensitive skin?

While Estradiol Gel is generally well-tolerated, it may cause skin irritation in some individuals, especially those with sensitive skin. It's essential to follow the instructions carefully and start with a small patch test to gauge your skin's reaction.

How often should I apply Estradiol Gel?

The frequency of application depends on your individual needs and the dosage prescribed by your doctor. Typically, Estradiol Gel is applied once or twice daily, but it's essential to follow the instructions carefully and consult with your doctor if you have any questions or concerns.

Can I use Estradiol Gel if I'm breastfeeding?

It's generally not recommended to use Estradiol Gel while breastfeeding, as it may pass into breast milk and affect the baby's health. Consult with your doctor to discuss alternative options and determine the best course of treatment.

What are the potential side effects of Estradiol Gel?

Common side effects of Estradiol Gel include skin irritation, nausea, and dizziness. In rare cases, it may cause more serious side effects, such as blood clots or stroke. It's essential to report any concerns or side effects to your doctor immediately.

Can I buy Estradiol Gel over-the-counter?

No, Estradiol Gel is a prescription medication that requires a doctor's prescription. You can't buy it over-the-counter, and it's essential to consult with your doctor to determine the best course of treatment for your individual needs.

How long does Estradiol Gel take to work?

The onset of action for Estradiol Gel is typically within a few days to a week, depending on the dosage and individual factors. However, it may take several weeks to a few months to achieve optimal symptom relief and improved overall health.

Can I use Estradiol Gel with other medications?

It's essential to consult with your doctor before using Estradiol Gel with other medications, as it may interact with certain medications or worsen certain health conditions.

How do I store Estradiol Gel?

Estradiol Gel should be stored at room temperature, away from direct sunlight and moisture. It's essential to follow the storage instructions carefully to maintain the medication's effectiveness.

check_circlePros

  • Easy to apply and measure doses
  • Significant reduction in hot flashes and mood swings
  • Convenient gel form, eliminating the need for oral medication
  • Effective in alleviating menopause symptoms
  • Easy to incorporate into my daily routine
  • Less expensive than other hormone replacement therapy options
  • Quickly absorbed into the bloodstream for fast symptom relief

cancelCons

  • Caused skin irritation, especially on sensitive areas
  • May not be suitable for everyone, especially those with sensitive skin
  • Requires regular check-ups to monitor estrogen levels and adjust dosage
  • May interact with other medications or worsen certain health conditions
  • Can be messy to apply, especially if not used carefully
  • May not be suitable for long-term use without close monitoring
  • May cause nausea and dizziness in some individuals

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